Former Staff Member

Dr. Ilse TINDEMANS



Research

Songbirds share with humans the capacity to produce complex vocalizations that are mostly learned from a tutor and enriched with improvisation, what makes them an interesting model to study the neural substrate for a complex learned behaviour. This vocal behaviour is controlled by a circuitry of connected brain region (called song nuclei) exclusively dedicated to song learning and production. Using manganese as a calcium analogue that can be taken up and transported by neurons and as a paramagnetic contrast agent, we want to visualize the distinct song nuclei with their projections and want to study the activity of the involved neurons upon song stimulation.

Publications

  • Applications of manganese-enhanced magnetic resonance imaging (MEMRI) to image brain plasticity in song birds.
    A. Van der Linden, V. Van Meir, I. Tindemans, M. Verhoye, J. Balthazart.
    NMR Biomed 17:8(2004), p.602-12.
  • In vivo dynamic ME-MRI reveals differential functional responses of RA- and area X-projecting neurons in the HVC of canaries exposed to conspecific song.
    I. Tindemans, M. Verhoye, J. Balthazart, A. Van der Linden.
    Eur J Neurosci 18:12(2003), p. 3352-60.
  • In vivo manganese-enhanced magnetic resonance imaging reveals connections and functional properties of the songbird vocal control system.
    A. Van der Linden, M. Verhoye, V. Van Meir, I. Tindemans, M. Eens, P. Absil, J. Balthazart.
    Neurosci 112:2(2002), p. 467-74.
  • Comparing BOLD fMRI signal changes in the awake and anaesthetised rat during electrical forepaw stimulation.
    R.R. Peeters, I. Tindemans., E. De Schutter, A. Van der Linden.
    Magn Reson Imaging 19:6(2001), p. 821-6.


Click here for the Academic Bibliography